The hypoglycemic effect of Juglans regia leaves aqueous extract in diabetic patients: A first human trial

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Study of Hypoglycemic Effect of Juglans regia Leaves and its Mechanism

  Background: Hypoglycemic effect of Juglans regia leaves was reported in other previous researches.   Objective: To investigate the mechanism of hypoglycemic action of Julans regia Leaves Methanolic Extract (JRLME), we designed the following study.   Methods: Male wistar rats were classified in five groups, each of six, including alloxan-induced diabetic rats treated with JRLME at doses of 250...

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Antioxidant and Hypoglycemic Effects of Tithonia diversifolia Aqueous Leaves Extract in Alloxan-induced Diabetic Mice

Diabetes is a chronic disease cause the metabolic disorder and associated with serious complications. Various studies have shown that diabetes mellitus is associated with increased the formation of free radicals and decreased antioxidant potential. Oxidative stress is increased in diabetes because of multiple factors. Dominant among these factors is glucose autoxidation leading to the productio...

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Anti-diabetic eff ects of an alcoholic extract of Juglans regia in an animal model

Aim: Many traditional treatments have been recommended in the alternative system of medicine for treatment of diabetes mellitus. Juglans regia is one of the medicinal plants used in traditional Iranian medicine as a treatment for diabetes, but little scientific documentation supports its antidiabetic action. Th e purpose of this study was to investigate antidiabetic eff ect of J. regia leaves i...

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Therapeutic potential of Juglans regia L. leaf extract against diabetic retinopathy in rat

Objectives Oxidative stress has a pivotal role in the pathogenesis of diabetic retinopathy (DR). Juglans regia L. (JRL) leaf extract has hypoglycemic and antioxidative properties. This study aimed to determine the ameliorative effects of JRL against diabetic retinopathy. Materials and Methods The DR rat model was generated by injection of streptozotocin (STZ). A subset of the diabetic rats re...

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ژورنال

عنوان ژورنال: DARU Journal of Pharmaceutical Sciences

سال: 2014

ISSN: 2008-2231

DOI: 10.1186/2008-2231-22-19